Polymyxin B Sulfate, a member of the polypeptide family, is an antibiotic primarily utilized for the treatment of bacterial infections, specifically those induced by gram-negative bacteria.
To ensure proper use of Polymyxin B Sulfate, it is crucial to follow the guidance of a medical professional and complete the entire prescribed treatment. Like any other antibiotic, this medication should not be used without a doctor's prescription to avoid misuse and subsequent development of antibiotic resistance. It is important to prioritize completing the full course of treatment to effectively treat the infection and prevent the need for additional treatments in the future.
Specification
Boiling point: 1651ºC at 760 mmHg
Molecular formula: C56H100N16O17S
Molecular weight: 1301.555
Flash point: 952.3ºC
Exact mass: 1300.717285
PSA: 573.64000
LogP: 2.54990
Vapor pressure: 0mmHg at 25℃
Applications
One of the most widely-used antimicrobial agents is Polymyxin B Sulfate, particularly for treating infections in the respiratory system, skin, and urinary tract. Its mode of action involves binding to the bacterial cell membrane and disrupting its integrity, causing it to lose essential components and succumb to death. Polymyxin B Sulfate is typically administered either through injection or topical application for maximum efficiency.
Why Use Polymyxin B Sulfate?
Polymyxin B Sulfate is an effective antibiotic agent that is known for its cationic surfactant properties. It is a potent mixture of polymyxins B1 and B2, both of which have the ability to enhance the permeability of cell membranes. As a polypeptide antibiotic, Polymyxin B showcases remarkable antibacterial activity against Gram-negative bacilli. By altering the structure of the membrane, this powerful antibiotic is effective in inhibiting the growth of Gram-negative bacteria. One of the most remarkable features of Polymyxin B is its ability to kill Escherichia coli, a common bacterium responsible for various infections.
Storage
To maintain its quality, the product must be kept in a cool and dry location, shielded from excessive light exposure and high temperatures. If the solution is reconstituted, it is advised to store it in the refrigerator for a maximum of 24 hours.
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