Enfuvirtide is an HIV fusion inhibitor
Specifications
| Appearance | White to off-white powder |
| Molecular Formula | C204H301N51O64 |
| Molar Mass | 4492.1 g/mol |
| Purity | ≥98% |
| Impurity | ≤0.5% |
Applications
The combination of reverse transcriptase drugs can be used to manage human immunodeficiency virus (HIV) infection effectively.
Why use Enfuvirtide?
Enfuvirtide is a synthetic peptide HIV fusion inhibitor that targets the viral envelope glycoprotein, preventing the necessary conformational changes required for the fusion of the virus and the host cell membrane. This ultimately leads to the inhibition of HIV-1 replication. The peptide has been developed based on an amino acid sequence found naturally in the HR2 domain of gp41. It mimics the activity of the HR2 domain, effectively competing with the HR1 domain and preventing the interaction between HR1 and HR2. As a result, the configuration of gp41 remains unchanged, preventing the fusion of the virus with the host cell. Enfuvirtide acts as a potent inhibitor of HIV-1 and is a promising therapeutic option for the treatment and prevention of HIV infection.
Storage Temperature: 2-8℃
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